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  • Action Air Duct Announces Specialized Cleaning Solutions for Unique Climate Challenges

    Action Air Duct Announces Specialized Cleaning Solutions for Unique Climate Challenges

    DENVER, CO October 06, 2025 – PRESSADVANTAGE –

    Action Air Duct, a Denver-based HVAC cleaning specialist, has announced enhanced service protocols specifically designed to address the unique air quality challenges faced by Colorado residents due to the state’s high altitude, dry climate, and increasing wildfire activity.

    The company has developed specialized techniques to combat the accelerated dust accumulation and allergen buildup that occurs in Denver’s dry climate, where indoor air circulation patterns differ significantly from those at sea level. These enhanced protocols address the particular challenges of maintaining clean air ducts in an environment where static buildup and dust circulation occur at higher rates than in other regions.

    Action Air Duct

    “Colorado’s unique environmental factors create distinct challenges for indoor air quality that require specialized attention,” said Tamir Bachner, a representative from Action Air Duct. “The combination of high altitude, extreme temperature swings, and increasing wildfire smoke exposure means that traditional duct cleaning methods often fall short of what Denver area homes and businesses actually need.”

    The enhanced service protocols incorporate advanced HEPA filtration systems and negative pressure technology to ensure complete removal of microscopic particles, including wildfire ash and smoke residue that can become trapped in ductwork for months or even years after exposure. The company’s technicians utilize video inspection technology to identify hidden contamination that might otherwise go undetected in standard cleaning procedures.

    Research indicates that professional duct cleaning can reduce respiratory triggers, a particularly important consideration for Colorado families dealing with allergies and asthma. The state’s dry air naturally increases static electricity, which attracts and circulates more dust particles through HVAC systems compared to more humid climates.

    Action Air Duct Cleaning services also address the energy efficiency concerns that arise from clogged ductwork. Clean air ducts can improve HVAC efficiency, potentially saving homeowners hundreds of dollars annually on heating and cooling costs. This efficiency gain becomes especially significant during Colorado’s extreme temperature variations, when heating and cooling systems must work harder to maintain comfortable indoor temperatures.

    The company’s comprehensive approach includes antimicrobial treatments to prevent future bacterial and mold growth, a critical consideration given Colorado’s dramatic temperature extremes that can create condensation issues within ductwork. Additionally, their technicians are trained to identify and report dangerous duct damage and leaks that could compromise system performance or indoor air quality.

    Action Air Duct serves residential and commercial clients throughout the Denver metro area, including Arvada, Aurora, Boulder, Broomfield, Castle Rock, Centennial, Englewood, Golden, Greenwood Village, Highlands Ranch, Lakewood, Littleton, Northglenn, Parker, Thornton, Westminster, and Wheat Ridge. The family-owned company has operated in the Denver area since 2014, maintaining a focus on professional, honest, and affordable service. Their team of certified technicians stays current with the latest equipment and cleaning methodologies to ensure optimal results for each client’s specific air quality needs.

    ###

    For more information about Action Air Duct, contact the company here:

    Action Air Duct
    Tamir Bachner
    720-257-3319
    tamir@actionairduct.net
    100 Fillmore St Suite 563
    Denver, CO 80206

  • FatPipe (FATN) Announces General Availability of Total Security 360 Single-Stack Integrated Cybersecurity Platform with SD-WAN and Network Security for SMB Market

    FatPipe (FATN) Announces General Availability of Total Security 360 Single-Stack Integrated Cybersecurity Platform with SD-WAN and Network Security for SMB Market

    Single-stack network, cybersecurity, and email security solution simplifies deployment

    SALT LAKE CITY, UT / ACCESS Newswire / October 6, 2025 / FatPipe, Inc. (NASDAQ:FATN) today announced broad availability of Total Security 360, a single-stack cybersecurity and networking platform that replaces the complexity of managing multiple security solution vendors with one integrated platform from FatPipe. Total Security 360 combines top-rated SD-WAN and Advanced Network Perimeter Security, Cybersecurity, Email Security, and deep packet inspection for regulatory compliance, including HIPAA, PCI, NIST, GDPR, MITRE ATT&CK, and others, within a unified architecture that is easier to deploy, monitor, and scale.

    “FatPipe offers an on-premise solution in addition to a cloud-based solution. The advantage of the on-premise solution is integrated network and cybersecurity, faster response to authentication, faster email sandboxing and delivery, and elimination of ISP jitter and latency that affects VPN connectivity, dropped packets, and response times,” said Ms. Sanch Datta, President and CTO. “With 90% of employees typically located on-premise in most SMB organizations, the need to go to the cloud for slow, delayed services is eliminated,” added Ms. Datta.

    SMB security teams are stretched by having to manage too many vendors, overlapping policies, and blind spots between various cyber services. Total Security 360 addresses these challenges with a consolidated platform that delivers the capabilities enterprises need out of the box: Advanced SD-WAN with Network protection, DDoS Mitigation and geo-fencing, NextGen Firewall, Intrusion Detection and Prevention, Deep Packet Inspection, Anti-virus and Data Loss Prevention, Email Sandboxing, integrated SIEM, for an advanced highly resilient network with application-aware connectivity, among other features.

    “SMB and Middle Market customers are tired of stitching together half a dozen security point solutions,” said Dr. Ragula Bhaskar, Chairman and CEO of FatPipe. “Total Security 360 gives customers a single-stack platform that is powerful, affordable, and simple to operate. For the price of a latte per employee per month, the customer gets full network and cyber security – One policy model, single pane of glass, and one vendor that is accountable for outcomes.”

    Key capabilities of Total Security 360

    • Unified Advanced Networking and cybersecurity: SD-WAN, NextGen Firewall, IDS/IPS, AV, DLP, DNS and URL controls, and DDoS protections operate as one system with shared intelligence.

    • Email Sandboxing: Email sandboxing analyzes suspicious attachments to help stop email-borne threats before they reach users.

    • Integrated SIEM: Centralized log collection, correlation, and alerting for network and security events improve investigation speed and audit readiness.

    • Resilient connectivity: Intelligent multi-path routing and automatic sub-second failover maintain application performance across broadband, fiber, and cellular links.

    • Central control: A single controller pushes consistent policies across sites, with real-time observability and compliance reporting.

    • Flexible deployment: On-prem, Cloud, and hybrid options support branch, campus, data center, and sovereign requirements.

    Availability
    Total Security 360 is available today through FatPipe and authorized partners. Existing FatPipe SD-WAN customers can add security capabilities under the same controller and policy framework. For pricing, demos, and partner information, contact sales123@fatpipeinc.com or visit fatpipeinc.com.

    About FatPipe
    FatPipe pioneered the concept of software-defined wide area networking (SD-WAN) and hybrid WANs that eliminated the need for cooperation from ISPs and allow companies and service providers to control multi-link network traffic worldwide. FatPipe has now pioneered cost-effective, advanced single-stack cybersecurity for on-premise deployments that significantly improve network and cybersecurity for SMBs.

    FatPipe holds 13 U.S. patents related to multipath, software-defined networking. FatPipe products are sold by 200+ resellers worldwide.

    Forward-Looking Statements
    Certain statements contained in this press release, including statements relating to the Company’s expectations regarding the completion, timing and size of its proposed public offering and listing may constitute forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements can generally be identified by our use of forward-looking terminology such as “may,” “will,” “expect,” “intend,” “anticipate,” “estimate,” “believe,” “continue,” or other similar words. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based on management’s current expectations and are inherently subject to various risks, uncertainties, assumptions, or changes in circumstances that are difficult to predict or quantify. These risks and uncertainties include, but are not limited to, risks and uncertainties associated with the consummation of the offering and other risks described in FatPipe’s registration statement on Form S-1, as it may be amended from time to time. Except as required by law, FatPipe expressly disclaims a duty to provide updates to forward-looking statements, whether as a result of new information, future events or other occurrences.

    For more information, visit www.fatpipe.com.

    Follow us on X @FatPipe_Inc.

    Company Contact Info
    Vikrant Ragula
    Director of Investor Relations
    +1 801.683-5656 x 1140
    Investor.ir@fatpipeinc.com
    press132@fatpipeinc.com

    SOURCE: FatPipe Networks

    View the original press release on ACCESS Newswire

  • Trust Consulting Services Named One of CIO Bulletin’s Global Best Companies

    Trust Consulting Services Named One of CIO Bulletin’s Global Best Companies

    WASHINGTON, DC / ACCESS Newswire / October 6, 2025 / Trust Consulting Services, a leading provider of digital workforce solutions, cybersecurity, AI/ML integration, and physical security services, is proud to announce that it has been recognized by CIO Bulletin as one of the Global Best Companies of the Year 2025.

    This prestigious recognition highlights Trust Consulting Services’ commitment to innovation, client success, and its role in driving digital transformation across government and commercial sectors.

    Since its founding, Trust Consulting Services has delivered mission-critical solutions to federal agencies, private enterprises, and nonprofit organizations. With a focus on bridging the gap between technology and people, the company has built a reputation for excellence in program management, acquisitions support, and secure technology enablement.

    “This award reflects the hard work of our entire team and our shared commitment to excellence,” said James W. Radford, CEO of Trust Consulting Services. “At Trust, we believe in combining cutting-edge digital solutions with the power of human talent to deliver results that make a measurable difference. Being recognized by CIO Bulletin as one of the Global Best Companies of the Year affirms our vision and inspires us to continue setting the standard in government contracting and digital innovation.”

    The CIO Bulletin Global Best Companies of the Year program celebrates organizations worldwide that demonstrate exceptional leadership, innovation, and performance. Honorees are selected for their impact on industry transformation, strong customer partnerships, and commitment to growth.

    Trust Consulting Services continues to expand its footprint across cybersecurity, AI/ML applications, and digital transformation initiatives. The company’s success is anchored in its mission to deliver trusted solutions that empower organizations to thrive in an evolving digital landscape.

    For more information, please contact:

    James Radford
    Chief Executive Officer
    Trust Consulting Services
    Email: info@trustconsultingservices.com
    Phone: (202) 770-1925

    SOURCE: Trust Consulting Services, Inc.

    View the original press release on ACCESS Newswire

  • Weymouth Libraries Foundation Funds New Study Pods at Tufts Library

    Weymouth Libraries Foundation Funds New Study Pods at Tufts Library

    Nonprofit aims to strengthen community with inclusive spaces for learning & connection

    WEYMOUTH, MA / ACCESS Newswire / October 6, 2025 / The Weymouth Libraries Foundation is the local nonprofit organization proudly funding the recent installation of three new Nook study pods at Tufts Library, enhancing the library’s ability to serve community members seeking quiet spaces for work, study, and collaboration.

    The pods, financed entirely through the Foundation’s community support initiatives, were just installed and are now available for public use. Two of the pods are labeled 221A and 222A, which are located in between the traditional study rooms 221 and 222. The specialized Sensory Nook has been placed in the back corner of the children’s room next to the existing study rooms.

    “These new pods represent our commitment to making Weymouth Libraries inclusive and accessible to all community members,” said Matt Tallon, President of the Weymouth Libraries Foundation. “The Foundation is proud to fund innovations that adapt to diverse needs, particularly with the sensory-friendly pod that will create a safe, calming space for children who may feel overwhelmed in traditional library settings.”

    The upstairs pods include a fully ADA-accessible Nook Shelter and a standard Nook Huddle. The Shelter features an open alcove design with a removable upper wall/whiteboard panel, built-in acoustic panels for sound control, and lockable casters for easy repositioning, making it highly accessible and adaptable. The Huddle pod accommodates up to 2 people with a table, integrated power strip, customizable lighting, removable upper wall/whiteboard panel, and under-seat storage. Both pods include built-in acoustic panels that create ideal environments for focused work while maintaining an open design.

    The Sensory Nook in the children’s room is specifically designed to support neurodiverse individuals, but it is open to all junior patrons who may need a sanctuary to focus, recharge, and connect with their surroundings in a supportive environment. This specialized pod features customizable lighting, soft acoustic panels to minimize noise, and creates a serene atmosphere that helps reduce anxiety and sensory overload. The mobile design allows library staff to reposition the pod as needed.

    “Tufts Library has established itself as one of the foremost modern libraries on the South Shore, and these pods further enhance our ability to support diverse learning needs,” said Amy Rosa, Weymouth Public Libraries Director. “The sensory-friendly pod in our children’s room will be particularly transformative, allowing us to better serve families whose children benefit from having a quieter, more controlled environment while still enjoying all the resources our library offers.”

    The Weymouth Libraries Foundation, an approved 501(c)(3) tax-exempt charitable organization, continues to focus on initiatives that promote the extraordinary resources and services offered by Weymouth’s public libraries. The Foundation believes that libraries play a vital role in connecting diverse community members across neighborhoods and providing dynamic resources for residents of all ages.

    Library patrons can reserve the pods through the Weymouth Public Libraries booking portal here or at the circulation desk during regular library hours.

    Later this year, the Weymouth Libraries Foundation has plans to deploy additional capital for an overhaul of the worn furniture in the Tufts Library’s children’s room, plus portable, outdoor rental lockers for the Franklin Pratt Library location.

    For more information about the Weymouth Libraries Foundation or to support future initiatives, please visit the website: www.weymouthlibrariesfoundation.org.

    About the Weymouth Libraries Foundation: The Weymouth Libraries Foundation, Inc. is an approved 501(c)(3) tax-exempt charitable organization committed to empowering our libraries to best serve and strengthen our community. The Foundation supports Weymouth Public Libraries in celebrating and sustaining the growth of community, collaboration, and culture through traditions of reading, learning, and sharing. For more information, visit www.weymouthlibrariesfoundation.org.

    Media Contact: Nina Pfister, Director of Communications, Weymouth Libraries Foundation at weymouthlibrariesfoundation@gmail.com

    SOURCE: Weymouth Libraries Foundation

    View the original press release on ACCESS Newswire

  • A $1 SIM Card Nearly Triggered America’s Zero Day; Here’s How SMX Could Stop the Next Attempt (NASDAQ: SMX)

    A $1 SIM Card Nearly Triggered America’s Zero Day; Here’s How SMX Could Stop the Next Attempt (NASDAQ: SMX)

    NEW YORK, NY / ACCESS Newswire / October 6, 2025 / It wouldn’t take a missile, a cyber army, or even a keystroke from a foreign power to break civilization. It could start with something worth less than a cup of coffee. A one-dollar SIM card.

    That’s the terrifying reality SMX (NASDAQ:SMX) was built to prevent. SMX’s molecular-marking technology embeds proof directly into the materials and hardware that keep the world connected, making every SIM, router, and sensor verifiable before it ever joins a live network. Because when authenticity fails, it isn’t a nuisance – it’s a countdown.

    When investigators in New York uncovered a hidden SIM-farmhundreds of servers and more than 100,000 counterfeit SIM cards-the discovery read like a footnote. It should have been front-page fear. Had that operation gone live, it could have flooded emergency networks with counterfeit signals, blocking 911 calls and choking the grid in noise. One minute of silence, and the country would have fallen into confusion that looked a lot like collapse.

    The Attack That Wouldn’t Look Like One

    If the lights went out for sixty seconds, the fallout wouldn’t wait. Hospitals would lose telemetry. Air traffic control would lose sync. Trading systems would halt, and markets would vaporize billions before anyone knew what happened. It doesn’t take destruction to cause devastation – it takes doubt.

    People should be scared. They nearly witnessed a modern fiction-to-fact Zero Day, and almost no one realized it. The only reason that SIM-farm didn’t become the most expensive minute in history is luck. Luck found it first through an unrelated “tip.” That’s not a strategy. That’s Russian roulette with global infrastructure.

    And it raises the harder question: how would the world even respond? A one-minute blackout wouldn’t get committees formed; it would get action. One could safely bet that the Trump administration wouldn’t wait for consensus or headlines; it would move swiftly, decisively, and perhaps unpredictably. That kind of posture makes escalation both more likely and more dangerous, because when rapid response replaces reflection, the margin for misunderstanding disappears. Panic would move faster than diplomacy could ever hope to.

    The Proof That Could Have Stopped The Threat

    SMX’s technology changes that equation. The company has the ability to embed molecular identifiers into the materials that make up critical infrastructure-routers, SIMs, sensors-and tie them to a digital ledger that verifies authenticity in seconds. Counterfeit parts can’t hide; they fail the test before they connect.

    If SMX’s system had been in place, that New York SIM-farm would have been a pile of inert plastic. Every fake card would have been flagged before activation, and each server quarantined before connection. Verification would have been instant, not post-attack forensic.

    Here’s the most important part: SMX isn’t a cybersecurity patch. It’s prevention at the molecular level. SMX’s model lets every component prove its identity before it’s trusted to operate. Proof becomes the gatekeeper. The counterfeit economy and cybercriminals are exposed not in the shadows of darkness but in the light.

    The Minute That Happily Changed Nothing

    The world dodged a digital bullet it never saw coming. That minute of darkness never arrived, but the message is clear: the world’s mightiest superpower is sometimes defended by luck, not strength.

    SMX removes that chance from the equation. By embedding proof into the materials that power civilization, it enables nations, telecoms, and utilities to verify authenticity before catastrophe strikes. It’s not about fear – it’s about realism.

    Because if a single dollar’s worth of counterfeit hardware can push the world to the edge of Zero Day, the only rational response is to make proof automatic. SMX makes that possible – with one mark, one scan, and no guesswork. That makes sure that the next time the lights flicker, no one will be looking for cover. They’ll just be looking for the replacement bulb.

    About SMX

    As global businesses face new and complex challenges relating to carbon neutrality and meeting new governmental and regional regulations and standards, SMX is able to offer players along the value chain access to its marking, tracking, measuring and digital platform technology to transition more successfully to a low-carbon economy.

    Forward-Looking Statements

    The information in this press release includes “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include, but are not limited to, statements regarding expectations, hopes, beliefs, intentions or strategies regarding the future. In addition, any statements that refer to projections, forecasts or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements. The words “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “forecast,” “intends,” “may,” “will,” “might,” “plan,” “possible,” “potential,” “predict,” “project,” “should,” “would” and similar expressions may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. Forward-looking statements in this press release may include, for example: matters relating to the Company’s fight against abusive and possibly illegal trading tactics against the Company’s stock; successful launch and implementation of SMX’s joint projects with manufacturers and other supply chain participants of gold, steel, rubber and other materials; changes in SMX’s strategy, future operations, financial position, estimated revenues and losses, projected costs, prospects and plans; SMX’s ability to develop and launch new products and services, including its planned Plastic Cycle Token; SMX’s ability to successfully and efficiently integrate future expansion plans and opportunities; SMX’s ability to grow its business in a cost-effective manner; SMX’s product development timeline and estimated research and development costs; the implementation, market acceptance and success of SMX’s business model; developments and projections relating to SMX’s competitors and industry; and SMX’s approach and goals with respect to technology. These forward-looking statements are based on information available as of the date of this press release, and current expectations, forecasts and assumptions, and involve a number of judgments, risks and uncertainties. Accordingly, forward-looking statements should not be relied upon as representing views as of any subsequent date, and no obligation is undertaken to update forward-looking statements to reflect events or circumstances after the date they were made, whether as a result of new information, future events or otherwise, except as may be required under applicable securities laws. As a result of a number of known and unknown risks and uncertainties, actual results or performance may be materially different from those expressed or implied by these forward-looking statements. Some factors that could cause actual results to differ include: the ability to maintain the listing of the Company’s shares on Nasdaq; changes in applicable laws or regulations; any lingering effects of the COVID-19 pandemic on SMX’s business; the ability to implement business plans, forecasts, and other expectations, and identify and realize additional opportunities; the risk of downturns and the possibility of rapid change in the highly competitive industry in which SMX operates; the risk that SMX and its current and future collaborators are unable to successfully develop and commercialize SMX’s products or services, or experience significant delays in doing so; the risk that the Company may never achieve or sustain profitability; the risk that the Company will need to raise additional capital to execute its business plan, which may not be available on acceptable terms or at all; the risk that the Company experiences difficulties in managing its growth and expanding operations; the risk that third-party suppliers and manufacturers are not able to fully and timely meet their obligations; the risk that SMX is unable to secure or protect its intellectual property; the possibility that SMX may be adversely affected by other economic, business, and/or competitive factors; and other risks and uncertainties described in SMX’s filings from time to time with the Securities and Exchange Commission.

    EMAIL: info@securitymattersltd.com

    SOURCE: SMX (Security Matters) Public Limited

    View the original press release on ACCESS Newswire

  • Steel Oak Coffee Launches First Interactive Coffee Flavor Wheel for Consumers

    Steel Oak Coffee Launches First Interactive Coffee Flavor Wheel for Consumers

    With 80% of Americans drinking coffee daily but only 10% choosing specialty, Steel Oak’s interactive Flavor Wheel helps consumers explore higher-quality options as rising commodity prices close the gap with specialty coffee.

    Oct. 7, 2025 / PRZen / ORMOND BEACH, Fla. — Steel Oak Coffee, a specialty coffee roaster based in Florida, has launched the first interactive Coffee Taster’s Flavor Wheel designed for consumers to shop coffee by taste.

    Traditionally reserved for coffee professionals and Q-graders, the Coffee Taster’s Flavor Wheel has been reimagined by Steel Oak Coffee into an intuitive retail tool. Visitors to the roaster’s website can explore categories like Floral, Fruity, or Chocolate, then instantly see coffees that match those sensory notes—making specialty coffee more approachable than ever.

    “Our goal was to bridge the gap between how roasters taste and how customers shop,” said Carl Dupper, CEO of Steel Oak Coffee. “This tool makes the professional flavor vocabulary both interactive and approachable, while guiding people to discover coffees that fit their palate.”

    Why It Matters

    More than 80% of Americans drink coffee daily, yet fewer than 10% choose specialty—a category defined by quality, traceability, and flavor depth. At the same time, the price of commodity coffee has risen 21% in the past year, narrowing the gap between mass-market blends and specialty beans. Unlike commodity coffee, specialty roasters such as Steel Oak are less impacted by tariffs and global price swings, allowing them to offer higher-quality coffee at prices now comparable to grocery store options.

    By connecting everyday drinkers directly to flavor-driven choices, Steel Oak Coffee’s interactive wheel makes specialty coffee accessible at a moment when consumers are primed to upgrade their daily cup.

    Key Highlights

    • First known interactive Coffee Taster’s Flavor Wheel in specialty coffee e-commerce
    • Consumers can shop by flavor preference instead of origin or roast level
    • Simplifies the buying process while encouraging exploration and education

    The interactive wheel is now live at https://steeloakcoffee.com/pages/coffee-flavor-wheel.

    About Steel Oak Coffee
    Founded in 2016 in Ormond Beach, Florida, Steel Oak Coffee is built on the pillars of integrity, authenticity, and community. The roaster sources seasonal, ethically grown beans and roasts them in small batches to highlight their true character and terroir. With a commitment to education, transparency, and innovation, Steel Oak Coffee continues to push the boundaries of consumer coffee experiences.

    Press Release Distributed by PRLog

    Source: Steel Oak Coffee

    Follow the full story here: https://przen.com/pr/33595008

  • BrYet US, Inc. Receives Approval to Initiate in Australia a First-in-Human Phase 1/2 Trial of ML-016 in Advanced Cancers with Lung and/or Liver Involvement

    BrYet US, Inc. Receives Approval to Initiate in Australia a First-in-Human Phase 1/2 Trial of ML-016 in Advanced Cancers with Lung and/or Liver Involvement

    HOUSTON, TX and SUNSHINE COAST, QUEENSLAND / ACCESS Newswire / October 6, 2025 / BrYet US, Inc. (“BrYet”), a biotechnology innovator developing a drug with the potential to be a first-in-class medicine for metastatic disease, today announced that it has received an Australian Human Research Ethics Committee (HREC) approval for its first-in-human clinical study of ML-016.

    The open-label, dose-escalation and expansion study, titled “A Phase 1/2 Study of ML-016 in Participants with Advanced Cancer with Lung and/or Liver Involvement,” is authorized to commence in Australia with the University of the Sunshine Coast (UniSC) Clinical Trials as the lead site. BrYet expects the trial enrollment to begin in early 2026. The drug, ML-016 is manufactured and formulated at NerPharMa in Nerviano, Italy.

    “Securing HREC approval is a critical milestone that brings us closer to providing hope of improved health to patients suffering from cancers of the lungs and liver, including metastatic lesions originating from other organs or tissue in the body,” said Dr. Mauro Ferrari, the President and CEO of BrYet. “Furthermore, it supports our innovative approach to oncology, based upon targeting the molecular transport phenotype of cancer lesions in the lungs and liver.”

    ML-016 comprises an amino acid polymer conjugated to doxorubicin, with a formulation that includes platelet-like bio-erodible mesoporous silicon elements, which target the vascular endothelium of blood vessels in the tumor microenvironment. The amino acid-drug conjugate is released into the tumor, where it forms exosome-like vesicles. These “exosomoids” are designed to be preferentially taken up by cancer cells including those that have previously been resistant to therapy.

    Through the mechanisms of cellular trafficking, the exosomoid vesicles are intended to be transported to late-stage endosomes and lysosomes, where the increased acidity releases the cytotoxic agent into the cell nucleus. In preclinical studies, BrYet demonstrated that by way of these combined mechanisms of action and transport, 50% of laboratory animals with otherwise uniformly lethal metastatic burden achieved long-term survival.

    The Phase 1 portion of the trial will evaluate the safety, tolerability, and pharmacokinetics of ML-016 and identify two doses recommended for expansion into Phase 2. The Phase 2 expansion portion of the trial will include disease specific cohorts planned to explore preliminary antitumor activity in advanced solid tumors involving the lungs and/or liver. The trial will be led by UniSC Principal Investigator Dr. Brenton Seidl who believes metastatic cancer involving the lungs or liver remains one of the most complex challenges in oncology.

    “This trial offers hope for those who have exhausted standard treatment options and allows us to investigate a potential new approach that may improve outcomes for patients with advanced solid cancers,” Dr Seidl said.

    ###

    About BrYet US, Inc.

    BrYet is a privately held biotechnology company developing potentially first-in-class therapies for patients suffering from cancers for which there is no current curative treatment. BrYet’s lead asset, ML-016, is being developed for cancers of the lungs and liver, including advanced primary malignancies and metastatic spread from primary cancer that originates in other organs or tissue of the body. The company’s fundamental belief is that upon localization in the lungs and liver, these cancers acquire molecular transport phenotypes that are conserved regardless of site of origin and are largely independent of molecular mutations and their continued evolution. BrYet designs multi-component new chemical entities and formulations, which are directed against the fundamental aspects of these cancer-associated, organ-specific transport phenotypes. The company’s proprietary platforms include the mesoporous silicon components, and the mathematical formalism for designing the multi-component drugs, termed Transport Oncophysics. BrYet believes that similar approaches may provide advances against other forms of presently incurable cancers, as well as other pathologies of the lungs and liver. For more information about BrYet, please visit the company’s website: https://bryetpharma.com/

    About UniSC Clinical Trials

    UniSC Clinical Trials operates a growing clinical trial site network across the Sunshine Coast and surrounding regions, including specialist oncology trial capabilities. UniSC Clinical Trials works with local and global medical experts and industry to bring advanced treatments and therapies to life, and make cutting-edge medical research accessible to everyone.​ For more information, visit https://www.usc.edu.au/community/unisc-clinical-trials-clinical-trial-site-network

    Safe-Harbor Statement

    This press release contains forward-looking statements concerning BrYet and its business. These statements are based on the beliefs of, assumptions made by, and information currently available to the company’s management. When used in this document, the words “expects,” “anticipates,” “estimates,” “intends,” “believes,” “plans,” “predicts,” “should,” “could,” “will,” and similar expressions are intended to identify forward-looking statements.

    Forward-looking statements are subject to risks and uncertainties that could cause actual results to differ from expectations. Factors that could contribute to these differences include the results of studies and clinical trials, regulatory approvals, challenges in clinical trials, the ability to retain employees, research and development expenses, reliance on third parties, intellectual property issues, competition, future funding needs, economic conditions, and other industry-specific risks. You should not place undue reliance on these statements, which are current as of the date of this press release. BrYet does not plan to update these statements unless legally required.

    Media & Investor Contact
    BrYet US, Inc.
    info@bryetpharma.com | bryetpharma.com
    2450 Holcombe Blvd., Suite 1520, Houston, Texas 77021, USA

    SOURCE: BrYet US Inc.

    View the original press release on ACCESS Newswire

  • Clicksfinity Unveils Global Platform Giving Users Access to Digital Advertising Campaigns Worldwide

    Clicksfinity Unveils Global Platform Giving Users Access to Digital Advertising Campaigns Worldwide

    LONDON, UK / ACCESS Newswire / October 6, 2025 / Clicksfinity Ltd, a London-based technology company, has announced the launch of its global platform that enables users worldwide to sponsor digital advertising campaigns and participate in their results.

    The platform works in a simple and transparent way: users select a campaign, define their contribution amount, and choose the duration of their sponsorship. Once the campaign concludes, they receive a share of the results proportional to their contribution and the length of participation.

    Our mission was to democratize access to the digital advertising market in a transparent and accessible way,” said David Thompson, Head of Communications at Clicksfinity. “Every marketing campaign generates measurable outcomes, and our platform allows users to participate in the process and observe how campaigns perform.

    Key Features of the Platform:

    • Global Accessibility – supports multiple currencies and languages across markets.

    • Variety of Campaigns – from short-term launches to long-term AI-managed packages.

    • Transparency & Flexibility – campaign results visible in real time via the user dashboard, with the option to reinvest or withdraw earnings at any time.

    • Flexible Sponsorship Options – users freely choose their contribution and duration.

    • Technology and Optimization – AI-driven tools enhance campaign efficiency.

    Clicksfinity emphasizes that it is not a financial instrument but a technology platform providing access to the mechanics of sponsoring advertising campaigns. Users receive remuneration proportional to their level of participation and the duration of their sponsorship.

    About Clicksfinity Ltd

    Clicksfinity is a London-based technology company specializing in digital advertising campaigns. Its platform provides global access to marketing sponsorship opportunities, combining innovative technology, transparency, and a simple operating model. The company aims to position itself as the go-to platform for democratizing access to digital advertising markets worldwide. For more information, visit clicksfinity.com

    Contact Information

    Clicksfinity Ltd
    info@clicksfinity.com
    +447429 917872

    .

    SOURCE: Clicksfinity

    View the original press release on ACCESS Newswire

  • Telomir Pharmaceuticals Announces New Findings in a Prostate Cancer Model Demonstrating Telomir-1 Also Resets DNA Methylation of Tumor Suppressor Genes Implicated in Two of the Most Persistent Challenges in Oncology-Metastasis and Treatment Resistance

    Telomir Pharmaceuticals Announces New Findings in a Prostate Cancer Model Demonstrating Telomir-1 Also Resets DNA Methylation of Tumor Suppressor Genes Implicated in Two of the Most Persistent Challenges in Oncology-Metastasis and Treatment Resistance

    Findings show that Telomir-1 restores the body’s natural tumor suppressor defenses by reversing abnormal DNA methylation of MASPIN and RASSF1A – genes that help block invasion, limit metastasis, and improve chemotherapy responsiveness in aggressive prostate cancer models.

    MIAMI, FLORIDA / ACCESS Newswire / October 7, 2025 / Telomir Pharmaceuticals, Inc. (NASDAQ:TELO) (“Telomir” or the “Company”), a preclinical-stage biotechnology company developing therapies that target epigenetic drivers of cancer, aging, and age-related disease, today announced new preclinical results showing that its investigational therapy Telomir-1 reactivated two of the body’s most important tumor suppressor genes, MASPIN (“tumor suppressor shield”) and RASSF1A (“guardian gene”; also called SERPINB5), through DNA methylation reset in prostate cancer models. By restoring the activity of these genes, Telomir-1 may help prevent cancer spread and improve chemotherapy response

    Key New Findings

    • MASPIN (“tumor suppressor shield”): MASPIN is a natural defense protein that blocks tumor invasion, regulates cell migration and angiogenesis, promotes apoptosis, and enhances treatment sensitivity. In an aggressive prostate-cancer model in vivo, MASPIN was silenced by DNA hypermethylation. Telomir-1 reversed the chemotherapy-induced DNA methylation to restore MASPIN activity, consistent with reactivation of this key tumor-suppressor pathway.

    • RASSF1A (“guardian gene”, also called SERPINB5):
      RASSF1A is a critical regulator of cell cycle brakes, apoptosis, and suppression of metastasis. It is commonly silenced in aggressive cancers by hypermethylation. Telomir-1 reduced RASSF1A methylation in a dose-dependent manner, with stronger effects when combined with chemotherapy.

    • Implication: These results suggest Telomir-1 may reactivate natural tumor defenses, counteract chemotherapy-induced resistance mechanisms, and help limit metastasis – two of the most persistent challenges in oncology.

    Why This Matters

    Metastasis is responsible for the vast majority of cancer deaths, and chemotherapy resistance remains a major barrier to durable responses. Tumors often silence genes like MASPIN and RASSF1A by hypermethylation to disable the body’s natural defenses.

    Telomir-1’s ability to reset DNA methylation, restore tumor suppressor activity, and synergize with chemotherapy provides a compelling preclinical rationale for its potential as a first-in-class epigenetic reset therapy in oncology.

    Scientific Perspective

    “The potential reactivation of MASPIN and RASSF1A by inhibition of hypermethylation is highly significant because these genes play a central role in blocking tumor invasion, uncontrolled growth, and metastasis,” said Dr. Itzchak Angel, CSA at Telomir. “By demonstrating that in addition to an effect on DNA methylation of other key proteins, such as STAT1 and CDKN2A, Telomir-1 can also reset DNA methylation and restore the function of these silenced tumor suppressors, we are providing strong mechanistic evidence that this drug candidate could address cancer at its epigenetic roots in a broader manner.”

    CEO Perspective

    “These results highlight Telomir-1’s potential to change the way we think about treating cancer and aging,” said Erez Aminov, CEO of Telomir. “Instead of only managing disease progression; Telomir-1 may reset the underlying epigenetic programs that drive tumor growth, resistance, and cellular decline. By reawakening the body’s natural defenses, this approach could mark a new era in medicine – one where we target the root biology of cancer and age-related disease.”

    Building on Prior Work

    Telomir-1 has previously demonstrated in preclinical studies:

    • Reactivating tumor suppressors such as STAT1 (immune surveillance), CDKN2A (cell cycle brake), and TMS1 (apoptosis mediator).

    • Histone demethylase inhibition: activity across JMJD3 (KDM6B), UTX (KDM6A), FBXL10 (KDM2B), FBXL11 (KDM2A), and the KDM5 family – enzymes long considered undruggable despite their central role in cancer, inflammation, and resistance.

    • Mitochondrial health restoration: improved energy production while reducing oxidative stress (ROS) and avoiding unwanted cell proliferation, suggesting relevance to cancer metabolism as well as Alzheimer’s, Parkinson’s, ALS, and Progeria.

    • Wnt “fuel line” modulation: modest Tankyrase inhibition that may cut off cancer’s growth signaling without telomere-shortening toxicity.

    • Selectivity advantage: sparing broad acetyltransferases such as GCN5L2, reducing systemic toxicity risk.

    • Telomere & aging benefits: elongated telomeres and reversal of epigenetic drift in accelerated-aging models.

    • Functional in vivo outcomes: ~50% tumor volume reduction and elimination of chemotherapy-related mortality in aggressive prostate cancer models.

    Together, these findings support Telomir-1’s emerging profile as a broad-spectrum epigenetic and metabolic reset therapy with potential applications across oncology, neurodegeneration, autoimmune disease, metabolic dysfunction, and aging.

    Next Steps

    Telomir is advancing Telomir-1 through preclinical development and IND-enabling studies. Additional evaluations are underway in prostate cancer and other aggressive tumor models where epigenetic silencing and metabolic dysfunction drive metastasis and treatment resistance.

    About Telomir Pharmaceuticals

    Telomir Pharmaceuticals, Inc. (NASDAQ: TELO) is a preclinical-stage biotechnology company developing small-molecule therapies that target the root causes of cancer, aging, and age-related diseases by resetting dysregulated epigenetic programs. The Company’s lead candidate, Telomir-1, is being advanced across oncology and longevity indications based on its differentiated ability to restore tumor suppressors, block undruggable enzymes, and reprogram gene control. For more information, visit www.telomirpharma.com.

    Cautionary Note Regarding Forward-Looking Statements

    This press release, statements of Telomir’s management or advisors related thereto, and the statements contained in the news story linked in this release contain “forward-looking statements,” which are statements other than historical facts made pursuant to the safe harbor provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These risks and uncertainties include, but are not limited to, the potential use of the data from our studies, our ability to develop and commercialize Telomir-1 for specific indications, and the safety of Telomir-1.

    Any forward-looking statements in this press release are based on Telomir’s current expectations, estimates and projections only as of the date of this release. These and other risks concerning Telomir’s programs and operations are described in additional detail in its Annual Report on Form 10-K for the fiscal year ended December 31, 2024, which are on file with the SEC and available at www.sec.gov. Telomir explicitly disclaims any obligation to update any forward-looking statements except to the extent required by law.

    Contact Information

    Helga Moya
    info@telomirpharma.com
    (786) 396-6723

    SOURCE: Telomir Pharmaceuticals, Inc

    View the original press release on ACCESS Newswire

  • Engage Fi Announces Leadership Transition to Drive Continued Growth and Client Engagement

    Engage Fi Announces Leadership Transition to Drive Continued Growth and Client Engagement

    ORLANDO, FL / ACCESS Newswire / October 6, 2025 / Engage fi today announced a planned leadership transition.

    Andres Pasantes
    Andres Pasantes
    President & CEO

    Jenn Addabbo, who co-founded Engage fi and has served as Chief Executive Officer, will transition to the role of Executive Chair of the Board. In this capacity, she will provide ongoing oversight and guidance while focusing on strengthening strategic client engagements.

    Succeeding her as President & CEO will be Andres Pasantes, who currently serves as President & Chief Operating Officer. In his role, Pasantes has overseen the company’s operations and strategic direction and will now assume full responsibility for leading the organization.

    “This transition allows me to focus on what I value most – nurturing the trusted relationships we’ve built with clients and supporting Engage fi’s long-term strategy,” said Addabbo. “Andres has already been leading so much of our success, and I have the deepest confidence in his ability to continue guiding this organization with vision, integrity, and a relentless commitment to our clients.”

    “I am truly honored to step into the President & CEO role,” said Pasantes. “Engage fi is more than an organization to me – it is a mission I am profoundly committed to, shaped by the dedication of our people and the trust of our clients. Jenn’s leadership and belief in our purpose have built a powerful foundation, and I am dedicated to carrying that legacy forward, strengthening our culture, and expanding the impact we deliver together.”

    About Andres Pasantes

    Andres Pasantes is a seasoned executive with more than 30 years of experience in the financial services industry. As a visionary leader with a proven record in operational leadership, client experience optimization, and technology transformation, Pasantes brings deep expertise in business operations and strategic planning, coupled with a forward-looking vision that drives innovation and enterprise growth.

    He began his career at NationsBank, later Bank of America, where he gained firsthand experience with large-scale banking operations and transformation. Pasantes has since collaborated with more than 1,000 financial institutions in areas including strategic planning, technology assessments, mergers, conversions, and digital transformation.

    Before joining Engage fi, he held senior roles at organizations such as Fiserv, Open Solutions Inc., FIS, and D+H, where he led innovation and transformation initiatives across the credit union and community banking sectors.

    Pasantes holds a bachelor’s degree in International Affairs from Florida State University. Based in Orlando, Florida, he enjoys fitness, travel, and quality time with his wife, Collette, and their sons, Nathaniel and Mathias.

    Closing Statement

    “As I step into this role, I am deeply mindful of the responsibility and privilege of leading Engage fi into its next chapter. Our future is not just about helping financial institutions adapt to change – it’s about inspiring transformation that creates lasting value for our clients, partners, and communities. I am committed to ensuring that Engage fi continues to be a catalyst for innovation, growth, and impact.”
    Andres Pasantes, President & CEO, Engage fi

    Contact Information

    Shannon Crandall
    Director of Marketing
    shannon.crandall@engagefi.com
    480-686-4253

    .

    SOURCE: Engage fi

    View the original press release on ACCESS Newswire